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Bikes Without Borders
Bikes Without Borders (BWB) is a non-profit group that aims to use bicycles and pedal powered machines to make the world a better place. They have many plans, one of which is to aid in designing a bike that is accessible to the developing world (low-cost, durable, can carrier large loads, etc. etc.) Of course, they need the help of designers to accomplish that goal.
BWB also want to design other pedal powered machines that will make life easier for those who need them. The bicycle powered water pump that is pictured here from MayaPedal - www.mayapedal.org/bicimaquinas_in.html - is a good example of that type of project (you can also see other interesting bicycle based machines designed to help the people of Guatemala on the MayaPedal website). These are real projects for real applications to address real need.